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5-Amino-1MQ is an oral NNMT (nicotinamide N-methyltransferase) inhibitor that works by blocking an enzyme that depletes cellular NAD+ and SAM

People who do not benefit from vitamin B12 naturally due to absorption disorders, such as kidney disease or gastrointestinal diseases

The mechanism operates through two parallel pathways

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Along those lines, a quick online search does not show that the FDA has even classified 5-amino-1MQ as generally regarded as safe, which is the first step in making it available as a supplement